We have several basic science focuses. Dr. Tippi MacKenzie (View Bio | MacKenzie Lab) leads the effort in maternal-fetal immunity, stem cell biology, and targeted cellular therapy for fetuses that may benefit from prenatal cellular transplant. directs studies in lung biology, specifically investigating congenital anomalies of the lung and acceleration of lung growth in diseases that cause pulmonary hypoplasia. Other basic laboratory efforts are aimed toward improving outcomes for prenatally diagnosed congenital anomalies such as spina bifida, gastroschisis and urinary tract obstruction.
Our translational research is largely focused on the accelerated development of novel techniques and tools for congenital and acquired diseases of fetuses, infants, and children. While many of the fetal interventions being applied around the world today were developed in our own Fetal Treatment and Pediatric Surgery Research Laboratory, we are constantly developing new tools and techniques in a variety of animal models.