"Innovation in medicine is driven by need, but also by the market,"
said Dr. Michael R. Harrison, the director emeritus of the Fetal
Treatment Center and the director of the Pediatric Device
Consortium, both at the University of California, San Francisco.
"Big markets have lots of folks developing devices, but small
markets like the pediatrics market don't."
Maternal Liver Grafts More Tolerable for Children with Rare Disease
UCSF Department of Surgery - November 16, 2012
Children with a rare, life-threatening disease that is the
most common cause of neonatal liver failure - biliary atresia -
better tolerate liver transplants from their mothers than from
their fathers, according to a UCSF-led
study......"This result is exciting because it supports the
concept that trafficking of cells between the mother and the fetus
has functional significance long after the pregnancy is over," said
senior author Tippi MacKenzie, M.D.,
assistant professor of pediatric surgery at UCSF and a fetal
surgeon at UCSF Benioff Children's Hospital. "This is a
topic we are actively studying both in animal models and in
patients who have fetal surgery. Practically speaking, this study
may allow us to counsel families in which both the mother and
father are willing and able to be a donor."
"Inside Surgery", The Department of Surgery Newsletter, Summer 2012
UCSF Department of Surgery - August 22, 2012
This issue of Inside Surgery describes several exciting
developments that are advancing our ability to provide outstanding
care for a range of patients including the new Hepatobiliary
Service, under the direction of Carlos
Corvera, M.D., which provides comprehensive,
multidisciplinary care for patients with liver and bile duct
disease. Other topics include updates on Endocrine
Surgery, San Fancisco General Hospital's Wraparound Project, and
notable rankings of our surgeons within U.S. News & World
Report annual update.
Magnet trial an attractive option for kids with sunken chest
Reuters - August 19, 2012
Surgeons at the UCSF Benioff Children's Hospital in San
Francisco are using magnets to reshape the breastbones of children
who suffer from Sunken Chest Syndrome. The technique is undergoing
phase 3 clinical trials, but the doctors hope to prove that long
term magnetic force is as effective and less painful than
The Society of Clinical Trials has named
UCSF's Management of Myelomeningocele Study (MOMS), a review of
prenatal versus postnatal surgery for myelomengingocele (spina
bifida), as its Trial of the Year. The study earned
recognition as an important clinical trial that overcame
difficulties and produced remarkable results.
Doctors call Vilma Zarate's role as an administrative analyst in
University of California, San Francisco's fetal surgery department
invaluable to both faculty and patients. For faculty, Zarate
carefully crafts grant and funding applications and coordinates
clinical trials. Patients, on the other hand, benefit from the
clear and thoughtful consent documents Zarate creates to help them
understand the risks of cutting-edge medicine.
Spina Bifida Study a "Huge Gamechanger for Fetal Surgery"
New York Times - February 09, 2011
For years, surgeons have been seeking ways of operating on
babies in the womb, reasoning that medical abnormalities are easier
to address while the fetus is still developing. Now, for the
first time, a large clinical trial has shown that fetal surgery can
also benefit infants with non life-threatening
conditions. The eight-year study reported in the New England Journal of Medicine, found
that babies born with myelomeningocele, the most common
form of spina bifida, a debilitating spinal abnormality,
were twice as likely to walk and experienced fewer
neurological problems with in
utero repair versus standard post-natal
Mother’s stem cells likely key to treating genetic disease before birth
UCSF News - January 18, 2011
UCSF researchers have tackled a decade-long scientific
conundrum, and their discovery is expected to lead to significant
advances in using stem cells to treat genetic diseases before
birth. Through a series of mouse model experiments, the research
team determined that a mother's immune response prevents a fetus
from accepting transplanted blood stem cells, and yet this response
can be overcome simply by transplanting cells harvested from the
Institute for Fetal and Neonatal Health 1st Annual Research Symposium
UCSF Pediatric Surgery - November 02, 2010
UCSF announces the formation of the Institute for Fetal and
Neonatal Health symposium brings together clinicians and basic
scientists involved in different aspects of development and fetal
Teen girls’ obesity surgery may raise birth defect risk
UCSF News - October 03, 2010
A report by Diana Farmer, MD*, (former) chief of pediatric
surgery at UCSF Benioff Children's Hospital, has highlighted a
possible link between gastric bypass surgery in adolescent girls
and an increased risk for neural tube defects in their future
Stopping curvature of the spine in kids usually requires a
series of painful operations to implant rods and screws to adjust
the spine. Even then, the results are often less than perfect.
However, a medical team at UCSF has developed a technique using
magnets that promises to do away with so many surgeries.
Michael Harrison M.D. Elected to Institute of Medicine
UCSF News - October 12, 2009
Michael Harrison M.D., a
renowned pioneer in fetal and
pediatric surgery, Professor Emeritus of Surgery
and Pediatrics, and Director Emeritus of
the Fetal Treatment Center at UCSF, has been elected
to the prestigious Institute of Medicine (IOM), one of
the U.S. National Academies. Membership in the IOM reflects
"the height of professional achievement and commitment to service"
and is reserved for those at the pinnacle of their field.
Dr. Alfred de Lorimier, a pioneer in pediatric
surgery and founder of the Division of Pediatric Surgery
at UCSF, has died. We owe much to his contributions
and express our heartfelt sympathies to his family.